A亚型禽白血病的遗传抗性位点与肉鸡重要经济性状的关联分析

doi:10.11843/j.issn.0366-6964.2019.04.005

畜牧兽医学报 ›› 2019, Vol. 50 ›› Issue (4): 721-726.doi: 10.11843/j.issn.0366-6964.2019.04.005

A亚型禽白血病的遗传抗性位点与肉鸡重要经济性状的关联分析

甘师仪, 王劼, 罗成龙, 瞿浩, 舒鼎铭*

广东省农业科学院动物科学研究所, 畜禽育种国家重点实验室, 广东省畜禽育种与营养研究重点实验室, 广州 510640

收稿日期:2018-09-25 出版日期:2019-04-23 发布日期:2019-04-23
通讯作者: 舒鼎铭,主要从事家禽遗传育种与产业化研究,E-mail:shudm@263.net
作者简介:甘师仪(1989-),女,湖北人,硕士,助理研究员,主要从事家禽遗传育种研究,E-mail:gan_shiyi@163.com
基金资助:
广东省自然科学基金（S2013030013313）；国家自然科学基金（31402064）；广东省科技计划（2017B020232003）；国家肉鸡产业技术体系专项（CARS-41）

Association of Genetic Resistance Loci to Subgroup A Avian Leukosis Virus with Important Economic Traits in Broilers

GAN Shiyi, WANG Jie, LUO Chenglong, QU Hao, SHU Dingming*

Guangdong Key Laboratory of Animal Breeding and Nutrition, State Key Laboratory of Livestock and Poultry Breeding, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China

Received:2018-09-25 Online:2019-04-23 Published:2019-04-23

摘要/Abstract

摘要：

为了研究A亚型禽白血病病毒遗传抗性与重要经济性状的关联性，本试验组建了肉鸡F₂代资源群体，在788只健康鸡中筛选了tva基因的抗性位点，分别测量记录每只鸡6、8、10、12周龄体重、屠宰体重、胸肌重、腿肌重等重要经济性状指标，并与tva基因位点进行关联分析。研究发现，在该试验群体中存在3个突变型tva^r3、tva^r5和tva^r6，命名为tva^mut502-516。通过关联分析发现，tva^mut502-516位点在屠体性状方面，只与腹脂重（AFW）和腹脂率（AFR）呈显著相关（P<0.05），与生长、饲料转化率及其他屠宰性状的相关性均未达到显著水平（P>0.05）。研究结果表明，A亚型禽白血病病毒的抗性遗传突变可以显著降低肉鸡的腹脂重（AFW）和腹脂率（AFR），并且对肉鸡的生长、饲料转化率等其他重要经济性状没有产生不良的影响，因此，该抗性位点可以兼顾抗性和生长发育，可应用于A亚型禽白血病抗病育种。

Abstract:

To investigate the association of genetic resistance loci to subgroup A avian leukosis virus(ALV) with important economic traits, the genetic variations within resistance loci of tva gene were screened in an F₂ resource population of broilers, which contained 788 healthy chicken. Production-related traits such as body weight, breast muscle weight, leg muscle weight on 6, 8, 10, 12 weeks and slaughter weight were measured, separately, and their association with genetic resistance loci to subgroup A avian leukosis virus was analyzed. Three variants (tva^r3, tva^r5 and tva^r6, named tva^mut502-516) were discovered in the F₂ population. Association analysis revealed that the tva^mut502-516 was significantly associated with abdominal fat weight (AFW) and abdominal fat rate (AFR) (P<0.05), but not significantly associated with growth, feed efficiency and other carcass traits (P>0.05). These results indicate that the mutation of genetic resistance loci to subgroup A avian leukosis virus can significantly decrease the AFW and AFR of chicken, and had no unfavorable effect on growth, feed efficiency and other carcass traits, therefore, these loci can balance the ALV-A resistance and growth development, can be applied in subgroup A ALV resistant breeding of broilers.

中图分类号:

S826.2

甘师仪, 王劼, 罗成龙, 瞿浩, 舒鼎铭. A亚型禽白血病的遗传抗性位点与肉鸡重要经济性状的关联分析[J]. 畜牧兽医学报, 2019, 50(4): 721-726.

GAN Shiyi, WANG Jie, LUO Chenglong, QU Hao, SHU Dingming. Association of Genetic Resistance Loci to Subgroup A Avian Leukosis Virus with Important Economic Traits in Broilers[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2019, 50(4): 721-726.

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A亚型禽白血病的遗传抗性位点与肉鸡重要经济性状的关联分析

Association of Genetic Resistance Loci to Subgroup A Avian Leukosis Virus with Important Economic Traits in Broilers

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